Bioinformatics Scientist

Job Locations US-MD-Gaithersburg
# of Openings
1
Category
NIAID
Type
Regular Full-Time
Min
USD $80,000.00/Yr.
Max
USD $101,000.00/Yr.

Overview

We are seeking a Bioinformatics Scientist to support the National Institutes of Health’s (NIH), world renowned National Institute of Allergy and Infectious Diseases (NIAID) in Gaithersburg, MD. Our NIAID professional, technical, and scientific support personnel are part of a preeminent team focused on positively impacting millions of lives around the world with groundbreaking research. Candidates will work at a prominent and vibrant NIAID worksite to directly support exciting ongoing research activities as a contractor team member. Accelerate your career and apply below to help us make a difference.

 

CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today’s most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.

 

Our employees enjoy a collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities

  • Support the Data Science & Automation group of the Vaccine Production Program (VPP) Labs of the Vaccine Research Center.
  • Work independently and collaboratively to develop or optimize wet lab procedures that improve the throughput of analytical and process development workflows such as chromatography screens, cell culture condition screens, process optimization, etc.
  • Implement and optimize wet lab high-throughput, quantitative analytical assays using methods such as colorimetric, fluorometric, and biolayer interferometry.
  • Design, test, and implement data transformation, integration, storage, and analysis pipelines, including development of custom programs written in Python, VBA, C/C++, etc.
  • Design and execute both wet lab and dry lab experiments that evaluate performance of process / analytical procedures.
  • Effectively communicate with other developers and functional team leads during design, optimization, and implementation of procedures / pipelines.
  • Prepare necessary materials (buffers, packed columns, reagents, etc.) in support of development activities.
  • Write and review technical protocols and reports.
  • Analyze and compile data, present at group/department meetings.
  • Other duties as assigned.

Qualifications

  • M.S degree in Chemistry, Biology, Biochemistry Life Sciences or a related discipline.
  • A minimum of five (5) years of experience in recombinant protein purification development for GMP clinical-phase products.
  • Demonstrated knowledge of maintaining accurate and detailed records.
  • Demonstrated expertise in the following techniques or tools for protein purification and characterization:
    • Column chromatography for protein purification by AEX, CEX, affinity, SEC, HIC.
    • Column packing and testing.
    • AKTA chromatography system.
    • Lab scale TFF systems.
    • Qualitative assays including SDS-PAGE and Western Blot.
    • UV/vis spectrophotometer.
  • Purification development experience for GMP process development in biotech/pharmaceutical or related industry (experience in clinical manufacturing is highly desirable).
  • Must be a team player who can effectively work with members from cross-functional departments.
  • Strong oral and written communication skills.
  • Familiarity with computer software including word processing and data evaluation.

Physical Requirements:

 

The physical requirements described here are representative of those that must be met by a candidate to perform the essential functions of this job. Reasonable accommodations may be provided to enable individuals with disabilities to perform essential job functions.

  • Constantly conduct sedentary work that primarily involves sitting/standing.
  • Occasionally perform work that includes moving objects up to 20 pounds, and perform work that includes moving objects up to 50 pounds.
  • Rarely perform heavy work that includes moving objects up to 100 pounds.
  • Occasionally push or pull less than 25 pounds and push or pull 25 – 45 pounds.
  • Occasionally reach above shoulder level.
  • Constantly use both hands.
  • Occasionally stand or walk for more than 25 minutes.
  • Occasionally bend, reach, or twist repeatedly and kneel, squat, or stoop.
  • Constantly have clear vision (near and/or far), depth perception, peripheral vision, and/or visual acuity.
  • Rarely move self in different positions to accomplish tasks in various environments including tight and confined spaces.
  • Occasionally move about to accomplish tasks or move from one worksite to another.
  • Constantly communicate with others to exchange information.
  • Constantly operate machinery and/or power tools.
  • Constantly assess the accuracy, neatness and thoroughness of the work assigned.
  • Rarely work in low or high temperatures.
  • Occasionally work in noisy environments.
  • Occasionally work in environments where no adverse conditions expected.
  • Constantly wear PPE including but not limited to gloves, face shields/goggles, safety glasses, safety shoes, lab coat and disposable dust/surgical mask.
  • Rarely wear ear plugs/muffs, clean room uniform and respirators, such as a disposable respirator mask (N-95), half-face/full-face style, PAPR, SCUBA.
  • Occasionally come in contact with chemicals, such as aerosols, biological inhalants, plastics, inorganic dust and powders, etc.

Please submit your resume online at www.CAMRIS.com. CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

 

CAMRIS offers a comprehensive benefits package, including medical, dental, and vision insurance for individuals and families, FSAs, HSA, life and AD&D insurance, short- and long-term disability, legal services, voluntary hospital indemnity, critical illness and accident insurances, EAP, pet insurance, 401(k) with employer match and Roth option, tuition and professional reimbursement, public transportation support in the DMV area, a referral bonus program, vacation with tenure-based increases, PTO, 11 paid holidays, paid bonding leave, and paid supplemental short-term disability.

 

Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.

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