Biologist - NIH - CIS/VRC

Job Locations US-MD-Bethesda
# of Openings
1
Type
Regular Full-Time

Overview

CAMRIS is a clinical and life sciences firm that realizes innovative solutions to challenges worldwide through high-quality, cost-effective program and research management services. We combine our proven systems with today’s most effective, evidence-based best practices to improve the lives of people around the world. Our core practice areas include HIV/AIDS, microbiology and infectious disease research, vaccine research, development and production, global health security, biodefense, and clinical research.

 

CAMRIS attracts the next generation of scientists to work at premier government research and development institutions with state-of-the-art facilities and equipment, under world leaders in health research. Our exceptional benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, Medical and Flexible Spending Accounts, and life insurance. If you enjoy being a part of a high performing health and research organization dedicated to making the world a healthier place, please apply today!

 

We are seeking a Biologist to support the mission of the Vaccine Research Center (VRC) at the National Institutes of Health (NIH) to:

Responsibilities

  • Perform a broad range of tasks related to evaluating vaccine efficacy in a nonhuman primate model of Mycobacterium tuberculosis (TB).
  • Perform a broad range of immunological assays related to the in vitro and in vivo evaluation of experimental TB vaccines: flow cytometry, confocal microscopy, Luminex, ELISA.
  • Isolate immune cells from a variety of animal or human blood and tissues under BSL2 and BSL3 lab conditions.
  • Perform (BSL3) assays that relate to quantifying mycobacterial burdens from animal tissues (culturing) and assessing anti-mycobacterial activity ex vivo following vaccination (ie, in vitro growth assays).
  • Oversee operations and maintain safety compliance of BSL-3 laboratory
  • Interact with scientists from other laboratories and institutions to implement protocols related to immunological and microbiological assays on tissues from Mtb-infected animals.
  • Interact with students, post-doctoral fellows and research technicians to provide training and standardization of BSL-3 protocols.
  • Conduct research independently including planning and executing experiments, overseeing animal protocols, data analysis and presentation, and peer reviewed publication of data.
  • Interact with scientists from other organizations or institutions involved in similar or related research projects.
  • Maintain organized and accurate, daily records of experiments and clearly communicate data to others.

Qualifications

  • Master’s degree in Immunology, Microbiology, or related field.
  • Minimum of four (4) years of technical experience working within a BSL-3 laboratory on the nonhuman primate model of Mycobacterium tuberculosis.
  • Extensive experience isolating immune cells from animal or human blood and tissues.
  • Extensive experience culturing and quantifying Mtb from infected animal tissues.
  • Ability to effectively train and oversee others on BSL-3 laboratory technique to comply with all safety regulations.
  • Experience evaluating antigen-specific cellular immune responses using multi-parameter flow cytometry, Luminex, ELISA.
  • Understanding of nonhuman primate or human T cell immunology as it relates to vaccine efficacy.
  • Demonstrated expertise in flow cytometry data analysis using FlowJo.
  • Computer skills to include MS Office Suite, GraphPad Prism.
  • Organization and written/verbal communication skills as to prepare written protocols, contribute to publications and communicate data to others.

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