Formulation Chemist - NIH - VRC

Job Locations US-MD-Bethesda
# of Openings
2
Type
Regular Full-Time

Overview

CAMRIS is a clinical and life sciences firm that realizes innovative solutions to challenges worldwide through high-quality, cost-effective program and research management services. We combine our proven systems with today’s most effective, evidence-based best practices to improve the lives of people around the world. Our core practice areas include HIV/AIDS, microbiology and infectious disease research, vaccine research, development and production, global health security, biodefense, and clinical research.

 

CAMRIS attracts the next generation of scientists to work at premier government research and development institutions with state-of-the-art facilities and equipment, under world leaders in health research. Our exceptional benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, Medical and Flexible Spending Accounts, and life insurance. If you enjoy being a part of a high performing health and research organization dedicated to making the world a healthier place, please apply today!

 

CAMRIS is seeking Formulation Chemists to support the mission of the Vaccine Research Center (VRC), within the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH) to:

Responsibilities

  • Design fit-for-purpose formulation and stability studies and lead execution of those studies.
  • Execute studies for the evaluation and development of stable formulations for the vaccine candidates at Vaccine Research Center (VRC), including the following subtasks
             o Generate samples for analysis using standard laboratory techniques (buffer prep, dialysis, dilution, etc.)
             o Analyze samples employing spectroscopic, calorimetric and other instrumentation.
             o Design studies in collaboration with team members.
             o Analyze, collate and interpret data in collaboration with team members.
  • Provide technical instruction to formulation team members.
  • Develop and execute assays for biological product characterization, formulation development and stability testing of recombinant protein-based vaccines, proteinaceous nanoparticles, and virus-like particles.
  • Present data in small group, department and conference settings.
  • Coordinate and execute routine maintenance and troubleshooting (problem diagnosis and repair) for laboratory instrumentation, including spectrometers, calorimeters, particle characterization and robotics systems.
  • Write and review technical reports and protocols documenting formulation, stability and method development studies.

Qualifications

  • B.S. or M.S. in Chemistry, Biochemistry, Chemical Engineering or a related discipline.
  • Minimum 2 years of industry, government or equivalent in protein formulation or a related field (Experience requirement may be waved for exceptional MS candidates)
  • Solid knowledge of the protein chemistry; understanding of biophysical and bioanalytical properties of proteins and biologics a plus.
  • Experience with protein spectroscopic analysis (UV-Vis, Fluorescence, Circular Dichroism spectroscopy).
  • Experience with classic protein biochemistry sample handling and analysis (UF/DF, SDS-PAGE, Western Blot).
  • Familiarity with data analysis software is required (Excel, Prism, SigmaPlot, etc.).

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