• Purification Manager, Head

    Job Locations US-MD-Silver Spring
    # of Openings
    Regular Full-Time
  • Overview

    CAMRIS International is an medical research and development firm that realizes innovative solutions to health and development challenges through high-quality, cost-effective program and research management services. We combine our proven systems with today’s most effective, evidence-based best practices to improve the lives of people around the world. Our core practice areas include HIV/AIDS, microbiology and infectious disease research, vaccine research, development and production, global health security, biodefense, and clinical research.


    CAMRIS is seeking a Purification Manager who will lead the Purification Section at a Bioproduction Facility in Silver Spring, MD.   S/he will perform duties associated with the downstream processing and purification of cells and cell products for use in human vaccines and biological products.


    *This is a forecasted position and it is contingent upon contract award. 


    • As a Section manager, directs the planning and scheduling of purification of desired products.
    • Make recommendations for purification of desired products based on research data received from research personnel. If necessary, will advise on further research to be conducted by appropriate personnel and/or work with the personnel to perfect purification processes. 
    • Responsible for perfecting purification procedures that will result in optimal recoveries. Starting materials will be concentrated suspensions of bacteria, yeast, mammalian cells, or insect cells. 
    • Depending on the desired product, will harvest cells intact, or when desired, process cells through various stages of downstream processing using appropriate equipment to accomplish this.
    • Write Standard Operating Procedures, Batch Production Records, and any other documents that are required to maintain documentation and compliance with current Good Manufacturing Procedures. 


    • MS degree in Biochemistry or the Life Sciences with at least 10 years’ experience in scaled purification.
    • Must have recent certification of training in GMP regulations.
    • Professional knowledge of the principles and practices applicable to purification and downstream processing of materials for vaccines destined for clinical testing.
    • Knowledge of operation of centrifuges (large and small-scale), ultrafiltration, and cell disruption equipment.
    • Knowledge of column chromatography and other purification methodologies.
    • Knowledge of facility support equipment such as water for injection, RODI water, and Hepa filtration HVAC systems.
    • Familiarity with related fields such as general microbiology, physical chemistry, and biochemistry.
    • Extensive knowledge of Good Manufacturing Practices as applied to biological products.
    • All proposed personnel to perform services contractor must verify employment eligibility (E-Verify) and obtain a favorable National Agency Check (NACI).


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